Genetics And Analysis Of Quantitative Traits Lynch Walsh Pdf

genetics and analysis of quantitative traits lynch walsh pdf

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Brings together the diverse array of theoretical and empirical applications of quantitative genetics.

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Evolution and Selection of Quantitative Traits

Quantitative traits—be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene—usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important.

Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, show Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models.

Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such.

This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields agriculture, evolution, ecology, and human biology as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection ranging from the use of genomic and historical data through to ecological field data and examining its consequences.

This extensive work of reference is suitable for graduate level students as well as professional researchers both empiricists and theoreticians in the fields of evolutionary biology, genetics, and genomics. It will also be of particular relevance and use to plant and animal breeders, human geneticists, and statisticians. Keywords: animal breeding , Bayesian analysis , behavioral genetics , detecting selection with marker data , ecological genetics , evolution , genomics , human genetics , mathematical modeling in biology , molecular evolution , natural selection , plant breeding , population genetics , quantitative genetics , statistical genetics.

Forgot password? Don't have an account? All Rights Reserved. OSO version 0. University Press Scholarship Online. Sign in. Not registered? Sign up. Publications Pages Publications Pages. Recently viewed 0 Save Search. Users without a subscription are not able to see the full content. Evolution and Selection of Quantitative Traits Bruce Walsh and Michael Lynch Abstract Quantitative traits—be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene—usually show considerable variation within and among populations.

More Quantitative traits—be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene—usually show considerable variation within and among populations.

Authors Affiliations are at time of print publication. The link was not copied. Your current browser may not support copying via this button. Show Summary Details. Subscriber Login Email Address. Password Please enter your Password. Library Card Please enter your library card number. View: no detail some detail full detail. I Introduction. Truncation and Threshold Selection. Permanent Versus Transient Response.

Changes in the Additive Variance. Changes in the Environmental Variance. Least-squares Approaches. Mixed-model and Bayesian Approaches. V Selection in Structured Populations. Deterministic Aspects. Finite Population Size and Mutation.

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Quantitative traits—be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene—usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important. Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, show Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields agriculture, evolution, ecology, and human biology as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics.


1st Volume: Genetics and Analysis of Quantitative Traits. You are visitor number, since 17 October The authors are Mike Lynch .


Evolution and Selection of Quantitative Traits

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Quantitative Trait Loci (QTL) Mapping

A quantitative trait locus QTL is a locus section of DNA that correlates with variation of a quantitative trait in the phenotype of a population of organisms. This is often an early step in identifying and sequencing the actual genes that cause the trait variation. A quantitative trait locus QTL is a region of DNA which is associated with a particular phenotypic trait , which varies in degree and which can be attributed to polygenic effects, i. The number of QTLs which explain variation in the phenotypic trait indicates the genetic architecture of a trait. It may indicate that plant height is controlled by many genes of small effect, or by a few genes of large effect.

Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: Lynch and B. Lynch , B. Walsh Published Biology. View PDF.

Protocol DOI: Quantitative trait loci QTL are genetic regions that influence phenotypic variation of a complex trait, often through genetic interactions with each other and the environment. These are commonly identified through a statistical genetic analysis. These are commonly identified through a statistical genetic analysis known as QTL mapping. Here, I present a step-by-step, practical approach to QTL mapping along with a sample data file. Antibody Data Search Beta. Authors: Kara E.


Genetics and Analysis of Quantitative Traits, By Michael Lynch and Bruce Walsh. Sunderland, MA: Sinauer Associates, Inc., Pp. $ (hardcover).


Introduction

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Quantitative Traits. Michael Lynch. Bruce Walsh Quantitative Genetics and Phenotypic Evolution. 4. Histórica! The nature of quantitative-trait variation.

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